Liver stiffness measurement predicts clinical outcomes in autoimmune hepatitis
The value of liver stiffness measurement as a predictor of outcomes in patients with autoimmune hepatitis (AIH) remains to be determined. In this large multicentre study, liver stiffness measurement was found to be an independent predictive factor of adverse clinical outcomes and cirrhosis development in AIH, irrespective of the achievement of biochemical response. A cut-off of 8.5 kPa accurately predicted cirrhosis development and poor outcomes in AIH.
Authors
- María Del Barrio (ORCID: https://orcid.org/0000-0002-6276-7405)
- George Ν. Dalekos (ORCID: https://orcid.org/0000-0001-7075-8464)
- Álvaro Díaz‐González (ORCID: https://orcid.org/0000-0003-3610-2263)
- Ignasi Olivas (ORCID: https://orcid.org/0009-0008-0766-6864)
- Stella Gabeta (ORCID: https://orcid.org/0000-0003-4779-8155)
- Sergio Rodríguez‐Tajes (ORCID: https://orcid.org/0000-0002-3189-7557)
- Mar Riveiro‐Barciela (ORCID: https://orcid.org/0000-0001-9309-2052)
- Sonia H. Torres (ORCID: https://orcid.org/0009-0003-6076-5136)
- Ezequiel Mauro (ORCID: https://orcid.org/0000-0002-0757-7676)
- María‐Carlota Londoño (ORCID: https://orcid.org/0000-0002-6533-1586)
- Pinelopi Arvaniti (ORCID: https://orcid.org/0000-0002-0278-3518)
- Kalliopi Zachou (ORCID: https://orcid.org/0000-0002-4218-9847)
- P. Pinon Esteban
Institutions
- Marqués de Valdecilla University Hospital (ES)
- University Hospital of Larissa (GR)
- Instituto de Investigación Marqués de Valdecilla (ES)
- Vall d'Hebron Hospital Universitari (ES)
- Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (ES)
- ERN GUARD-Heart (NL)
- Fundació Clínic per a la Recerca Biomèdica (ES)
- ERN RARE-LIVER (DE)
Publication Details
- Journal
- JHEP Reports
- Published
- 2024-09-06
- DOI
- https://doi.org/10.1016/j.jhepr.2024.101213
- Citations
- 11
- Primary Topic
- Liver Diseases and Immunity
- Type
- article
- Field-Weighted Citation Impact
- 4.06
Funders
- Instituto de Salud Carlos III