The pro-atherogenic enzyme PAPP-A is active in eluates from human carotid and femoral atherosclerotic plaques
This study provides evidence for the presence of enzymatically active PAPP-A in atherosclerotic plaques and underscores the need for further investigating potential beneficial effects associated with targeting PAPP-A in atherosclerotic cardiovascular disease.
Authors
- Lars Melholt Rasmussen (ORCID: https://orcid.org/0000-0001-5795-4794)
- Lasse Bach Steffensen (ORCID: https://orcid.org/0000-0001-6353-4227)
- A. K. Pedersen (ORCID: https://orcid.org/0000-0002-3202-2269)
- Claus Oxvig (ORCID: https://orcid.org/0000-0002-4715-9719)
- Mette Bjerre (ORCID: https://orcid.org/0000-0002-5511-8829)
- Mette Faurholdt Gude (ORCID: https://orcid.org/0000-0002-0653-093X)
- Rikke Hjortebjerg (ORCID: https://orcid.org/0000-0001-8237-0889)
- Jan Frystyk (ORCID: https://orcid.org/0000-0002-1481-3278)
Institutions
- Steno Diabetes Centers (DK)
- University of Southern Denmark (DK)
- Aarhus University (DK)
- Odense University Hospital (DK)
Publication Details
- Journal
- Atherosclerosis Plus
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1016/j.athplu.2024.09.001
- Citations
- 3
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.70
Funders
- Aarhus Universitet
- Aarhus Universitetshospital
- Novo Nordisk
- Danmarks Frie Forskningsfond
- Novo Nordisk Fonden