Contact X-ray Brachytherapy as a sole treatment in selected patients with early rectal cancer – Multi-centre study
CXB treatment alone achieved a high cCR rate with satisfactory LC and DFS. Inferior oncological outcomes were observed in patients who had received prior pelvic radiotherapy. CXB alone, with its favourable toxicity profile and avoidance of general anaesthesia and surgery risks, therefore, can be considered for patients who are unsuitable for or refuse surgery.
Authors
- Rajaram Sripadam (ORCID: https://orcid.org/0000-0003-4021-0611)
- Arthur Sun Myint (ORCID: https://orcid.org/0000-0001-5323-5696)
- A.S. Dhadda (ORCID: https://orcid.org/0000-0003-3561-3811)
- D. Mark Pritchard (ORCID: https://orcid.org/0000-0001-7971-3561)
- Muneeb Ul Haq (ORCID: https://orcid.org/0000-0002-2303-7469)
- Helen Minnaar (ORCID: https://orcid.org/0000-0002-6340-5641)
- Carrie A. Duckworth (ORCID: https://orcid.org/0000-0001-9992-7540)
- Calin Radu
- Kai Yu (ORCID: https://orcid.org/0000-0003-0098-1876)
- Joakim Folkesson
- Helen Wong (ORCID: https://orcid.org/0000-0002-2088-8401)
- Mark Halling‐Brown
- Alexandra Stewart (ORCID: https://orcid.org/0000-0001-9283-1327)
- David M. Hughes (ORCID: https://orcid.org/0000-0002-1287-9994)
- James L. Mills (ORCID: https://orcid.org/0000-0003-4496-332X)
- Ngu Wah Than (ORCID: https://orcid.org/0000-0003-4991-5431)
Institutions
- Uppsala University (SE)
- Nottingham University Hospitals NHS Trust (GB)
- Uppsala University Hospital (SE)
- University of Liverpool (GB)
- Royal Surrey County Hospital (GB)
- Castle Hill Hospital (GB)
- Nottingham City Hospital (GB)
- University of Surrey (GB)
- Clatterbridge Cancer Centre NHS Foundation Trust (GB)
- Health Data Research UK (GB)
Publication Details
- Journal
- Clinical and Translational Radiation Oncology
- Published
- 2024-09-06
- DOI
- https://doi.org/10.1016/j.ctro.2024.100851
- Citations
- 2
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.57
Funders
- European Commission
- H2020 Marie Skłodowska-Curie Actions