Vaccine optimization for highly pathogenic avian influenza: Assessment of antibody responses and protection for virus-like particle vaccines in chickens
The study demonstrated the immunogenic potential of the VLP vaccine in chickens. Our findings offer insights for optimizing VLP vaccines, allowing the incorporation of the HA of currently circulating H5 viruses to effectively mitigate the impact of the rapidly evolving clade 2.3.4.4 H5 outbreaks.
Authors
- Chia‐Chi Ku (ORCID: https://orcid.org/0000-0002-5740-1505)
- Min-Shi Lee (ORCID: https://orcid.org/0000-0001-5914-3370)
- Cheng‐Yu Lin (ORCID: https://orcid.org/0000-0002-7985-1611)
- Pei‐Wen Hsiao (ORCID: https://orcid.org/0000-0002-3589-6754)
- P Wang
- Chin-Rur Yang (ORCID: https://orcid.org/0000-0002-0178-7744)
- Shu‐Mei Liang
- Yi-Te Lin (ORCID: https://orcid.org/0000-0001-5282-4501)
- Po-Ling Chen (ORCID: https://orcid.org/0000-0002-7179-6144)
- Yu‐Chih Yang
Institutions
- National Health Research Institutes (TW)
- National Taiwan University (TW)
- Agricultural Biotechnology Research Center, Academia Sinica (TW)
Publication Details
- Journal
- Vaccine X
- Published
- 2024-09-06
- DOI
- https://doi.org/10.1016/j.jvacx.2024.100552
- Citations
- 3
- Primary Topic
- Influenza Virus Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Academia Sinica