Evaluation of Echocardiographic Parameters for Left Ventricle Systolic and Diastolic Dysfunctioni in Patients with Liver Cirrhosis

Prevalence of cirrhotic cardiomyopathy is an issue hard to estimate, both nationally and worldwide. This clinical research sets out a more precise evaluation of systolic and diastolic functions in cirrhotic patients using proved parameters - the TEI Index- to estimate systolic and diastolic dysfunction and the E/Vp ratio for diastolic dysfunction. These parameters were compared with classic parameters typically employed. Study population was represented by 70 patients diagnosed with liver cirrhosis.Results showed increased sensitivity of the TEI Index - in detecting systolic dysfunction in cirrhotic patients, with an increased accuracy compared to left ventricular ejection fraction. Regarding the parameters for diastolic dysfunction, it was proved that E/Vp ratio, had an increased specificity in detecting diastolic dysfunction due to cirrhotic cardiomyopathy. In conclusion, the hypothesis that patients with liver cirrhosis could benefit from an improvement of diagnostic sensitivity of cirrhotic cardiomyopathy using the two suggested parameters was confirmed in our study. And more important, a significant positive correlation between the severity of diastolic dysfunction and the severity of liver disease was found.

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Publication Details

Journal
Bulletin of the Transilvania University of Brasov Series VI Medical Sciences
Published
2024-09-05
DOI
https://doi.org/10.31926/but.ms.2024.66.17.2.1
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
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article

Evaluation of Echocardiographic Parameters for Left Ventricle Systolic and Diastolic Dysfunctioni in Patients with Liver Cirrhosis

E.G. Condrea, Daniel S. Lupu, Cristina Stănescu, A. Stoica et al.
Bulletin of the Transilvania University of Brasov Series VI Medical Sciences
Liver Disease Diagnosis and Treatment
article

Evaluation of Echocardiographic Parameters for Left Ventricle Systolic and Diastolic Dysfunctioni in Patients with Liver Cirrhosis

E.G. Condrea, Daniel S. Lupu, Cristina Stănescu, A. Stoica, L. Nedelcu
article en

Abstract

Prevalence of cirrhotic cardiomyopathy is an issue hard to estimate, both nationally and worldwide. This clinical research sets out a more precise evaluation of systolic and diastolic functions in cirrhotic patients using proved parameters - the TEI Index- to estimate systolic and diastolic dysfunction and the E/Vp ratio for diastolic dysfunction. These parameters were compared with classic parameters typically employed. Study population was represented by 70 patients diagnosed with liver cirrhosis.Results showed increased sensitivity of the TEI Index - in detecting systolic dysfunction in cirrhotic patients, with an increased accuracy compared to left ventricular ejection fraction. Regarding the parameters for diastolic dysfunction, it was proved that E/Vp ratio, had an increased specificity in detecting diastolic dysfunction due to cirrhotic cardiomyopathy. In conclusion, the hypothesis that patients with liver cirrhosis could benefit from an improvement of diagnostic sensitivity of cirrhotic cardiomyopathy using the two suggested parameters was confirmed in our study. And more important, a significant positive correlation between the severity of diastolic dysfunction and the severity of liver disease was found.

Bulletin of the Transilvania University of Brasov Series VI Medical Sciences
University of Medicine and Pharmacy of Craiova (RO), Transylvania University of Brașov (RO)
Openalex Percentile: Top 78%
Liver Disease Diagnosis and Treatment
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Evaluation of Echocardiographic Parameters for Left Ventricle Systolic and Diastolic Dysfunctioni in Patients with Liver Cirrhosis — E.G. Condrea, Daniel S. Lupu, et al. · Bulletin of the Transilvania University of Brasov Series VI Medical Sciences (2024) | TGRS Research Map | TGRS