Tert‐butylhydroquinone promotes skin flap survival by inhibiting oxidative stress mediated by the Nrf2/HO‐1 signalling pathway
In summary, TBHQ promoted flap survival in rats by up-regulating the Nrf2/HO-1 signalling pathway. As TBHQ is already widely used as a food additive, it could offer an acceptable means of improving clinical outcomes following skin flap surgery in patients.
Authors
- Jiapeng Deng (ORCID: https://orcid.org/0000-0002-0332-9296)
- Kaitao Wang
- Jialong Yang (ORCID: https://orcid.org/0000-0002-3112-5012)
- Qingyu Chen (ORCID: https://orcid.org/0009-0007-7975-0953)
- An Wang (ORCID: https://orcid.org/0000-0002-7027-6614)
- Guodong Chen
- Dingsheng Lin
- Minle Ye
Institutions
- Wenzhou Medical University (CN)
- Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University (CN)
Publication Details
- Journal
- British Journal of Pharmacology
- Published
- 2024-09-04
- DOI
- https://doi.org/10.1111/bph.17321
- Citations
- 6
- Primary Topic
- Wound Healing and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.50
Funders
- Wenzhou Medical University
- National Natural Science Foundation of China