Complete laparoscopic management of locally recurrent renal cell carcinoma after radical nephrectomy

Objective: Description of the laparoscopic approach for local recurrence of renal cell carcinoma after radical nephrectomy and oncological outcomes. Study design: A retrospective cohort analysis. Materials and methods: A retrospective cohort analysis included patients who underwent laparoscopic resection for RCC recurrence at XXX. The laparoscopic technique utilized either transabdominal or retroperitoneal approaches. The primary outcome measure was disease-free survival. Secondary outcome measures included operative time, estimated blood loss, and complications. Results: Thirteen patients underwent laparoscopic resection, with a mean operative time of 189 minutes and low complication rates. Pathological reports confirmed clear-cell RCC in the majority of cases. The median time to recurrence post-nephrectomy was 67 months, with a 3-year disease-free survival rate of 85%. All patients had negative margins, and at the last follow-up all patients were alive. Limitations: The limitations of this study include its small sample size and retrospective design. Value: The full laparoscopic approach for patients with local recurrence of renal cell carcinoma. Conclusion: Laparoscopic resection of locally recurrent RCC post-radical nephrectomy appears to be safe and effective, demonstrating promising oncological outcomes. Larger prospective studies are warranted to validate these findings and establish standardized guidelines for widespread implementation.

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Publication Details

Journal
Revista Mexicana de Urología
Published
2024-09-05
DOI
https://doi.org/10.48193/4s2h3424
Primary Topic
Renal cell carcinoma treatment
Type
article
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article

Complete laparoscopic management of locally recurrent renal cell carcinoma after radical nephrectomy

Gustavo Villoldo, G Candia, Juan Jorge Camean, Joaquín Chemi et al.
Revista Mexicana de Urología
Renal cell carcinoma treatment
article

Complete laparoscopic management of locally recurrent renal cell carcinoma after radical nephrectomy

Gustavo Villoldo, G Candia, Juan Jorge Camean, Joaquín Chemi, Jorge Jaunarena, Roberto Villalba Bachur
article en

Abstract

Objective: Description of the laparoscopic approach for local recurrence of renal cell carcinoma after radical nephrectomy and oncological outcomes. Study design: A retrospective cohort analysis. Materials and methods: A retrospective cohort analysis included patients who underwent laparoscopic resection for RCC recurrence at XXX. The laparoscopic technique utilized either transabdominal or retroperitoneal approaches. The primary outcome measure was disease-free survival. Secondary outcome measures included operative time, estimated blood loss, and complications. Results: Thirteen patients underwent laparoscopic resection, with a mean operative time of 189 minutes and low complication rates. Pathological reports confirmed clear-cell RCC in the majority of cases. The median time to recurrence post-nephrectomy was 67 months, with a 3-year disease-free survival rate of 85%. All patients had negative margins, and at the last follow-up all patients were alive. Limitations: The limitations of this study include its small sample size and retrospective design. Value: The full laparoscopic approach for patients with local recurrence of renal cell carcinoma. Conclusion: Laparoscopic resection of locally recurrent RCC post-radical nephrectomy appears to be safe and effective, demonstrating promising oncological outcomes. Larger prospective studies are warranted to validate these findings and establish standardized guidelines for widespread implementation.

Revista Mexicana de UrologíaVol. 84(4)
Instituto Alexander Fleming (AR)
Openalex Percentile: Top 73%
Renal cell carcinoma treatment
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