Predictive factors and survival outcome of conversion therapy for unresectable hepatocellular carcinoma patients receiving atezolizumab and bevacizumab: Comparative analysis of conversion, partial response and complete response patients

Patients with low tumour burden and low value of NLR were more likely to undergo conversion therapy. The OS of patients undergoing conversion therapy showed better survival compared to those achieving PR and was comparable to those with CR patients. Conversion therapy could be considered if feasible.

Authors

Institutions

Publication Details

Journal
Alimentary Pharmacology & Therapeutics
Published
2024-09-04
DOI
https://doi.org/10.1111/apt.18237
Citations
11
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
Field-Weighted Citation Impact
4.06
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Predictive factors and survival outcome of conversion therapy for unresectable hepatocellular carcinoma patients receiving atezolizumab and bevacizumab: Comparative analysis of conversion, partial response and complete response patients

Hideko Ohama, Norio Itokawa, Joji Tani, Kazunari Tanaka et al.
11 citations
Alimentary Pharmacology & Therapeutics
Hepatocellular Carcinoma Treatment and Prognosis
4.06
article

Predictive factors and survival outcome of conversion therapy for unresectable hepatocellular carcinoma patients receiving atezolizumab and bevacizumab: Comparative analysis of conversion, partial response and complete response patients

Hideko Ohama, Norio Itokawa, Joji Tani, Kazunari Tanaka, Yuki Kanayama, Tomomitsu Matono, Kazuhito Kawata, Kazuya Kariyama, Hidenori Toyoda, Hirayuki Enomoto, Kazuhiro Nouso, Takeshi Hatanaka, Masatoshi Kudo, Yoichi Hiasa, Kunihiko Tsuji, Atsushi Hiraoka, Takashi Kumada, Shinya Fukunishi, Tomomi Okubo, Takuya Nagano, Ei Itobayashi, Masaki Kaibori, Masashi Hirooka, Hiroki Nishikawa, Hisashi Kosaka, Kazuto Tajiri, Takashi Nishimura, Toshifumi Tada, Atsushi Naganuma, Akemi Tsutsui, Hidekatsu Kuroda, Toru Ishikawa, Yutaka Yata, Masanori Atsukawa, Tomoko Aoki, Fujimasa Tada, Asahiro Morishita, Koichi Takaguchi, Michitaka Imai, Satoru Kakizaki, Shinichiro Nakamura, Taeang Arai, Chikara Ogawa
article en
11 citations

Abstract

Patients with low tumour burden and low value of NLR were more likely to undergo conversion therapy. The OS of patients undergoing conversion therapy showed better survival compared to those achieving PR and was comparable to those with CR patients. Conversion therapy could be considered if feasible.

Alimentary Pharmacology & TherapeuticsVol. 60(10)
Kansai Medical University (JP), Gunma University (JP), Iwate Medical University (JP), Kagawa University (JP), Hamamatsu University School of Medicine (JP), Takamatsu Red Cross Hospital (JP), Saiseikai Niigata Daini Hospital (JP), National Hospital Organization Takasaki Medical Center (JP), Ogaki Municipal Hospital (JP), Himeji Medical Center (JP), Hanwa Memorial Hospital (JP), Gunma Saiseikai Maebashi Hospital (JP), Himeji Red Cross Hospital (JP), Teine Keijinkai Hospital (JP), Asahi General Hospital (JP), Toyama University Hospital (JP), Ehime Prefectural Central Hospital (JP), Kagawa Prefectural Central Hospital (JP), Takarazuka City Hospital (JP), Ehime University (JP), Gifu Kyoritsu University (JP), Nippon Medical School (JP), Osaka University of Pharmaceutical Sciences (JP), Kindai University (JP)
Good health and well-being
Openalex Percentile: Top 5%
Hepatocellular Carcinoma Treatment and Prognosis
4.06
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.