CCL4/CCR5 regulates chondrocyte biology and OA progression
The study highlights the critical role of CCL4/CCR5 in modulating chondrocyte apoptosis and ROS levels in OA progression. Targeting this pathway may offer promising therapeutic interventions for mitigating the pathogenic mechanisms associated with OA.
Authors
- Hongjian Deng
- Wei Liu (ORCID: https://orcid.org/0000-0001-7118-815X)
- Yuntao Wang (ORCID: https://orcid.org/0000-0003-1805-1247)
- Pengfei Xue (ORCID: https://orcid.org/0000-0002-9877-9360)
- Xiaogang Zhou
Institutions
- Southeast University (CN)
Publication Details
- Journal
- Cytokine
- Published
- 2024-09-05
- DOI
- https://doi.org/10.1016/j.cyto.2024.156746
- Citations
- 4
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.88