Assessment of NanoString technology as a tool for profiling circulating miRNA in maternal blood during pregnancy
Our results suggest that user-defined variables greatly influence the output of the assay. This highlights the need for standardised nSolver data analysis methods and detailed reporting of these methods. We suggest that investigators in the future should not rely on a single analysis method to identify changes and should always validate screening results.
Authors
- Iain M. Dykes (ORCID: https://orcid.org/0000-0002-1030-3721)
- Petra Adamova (ORCID: https://orcid.org/0000-0002-7213-0547)
- Andrew K. Powell (ORCID: https://orcid.org/0000-0002-3680-9384)
Institutions
- Liverpool John Moores University (GB)
Publication Details
- Journal
- Extracellular Vesicles and Circulating Nucleic Acids
- Published
- 2024-09-05
- DOI
- https://doi.org/10.20517/evcna.2024.38
- Citations
- 1
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.29