Circulating microRNAs targeting coagulation and fibrinolysis in patients with severe COVID-19
COVID-19 patients differentially express miRNAs with target genes involved in fibrinolysis inhibition, coagulation activity, and increased inflammatory response. These findings support the notion that COVID-19 widely affects hemostasis, including platelets, coagulation and fibrinolysis.
Authors
- Marja Lemponen
- Katariina Immonen
- Päivi Lakkisto (ORCID: https://orcid.org/0000-0001-9935-6573)
- Lotta Joutsi‐Korhonen (ORCID: https://orcid.org/0000-0002-7355-2354)
- Tuukka Helin (ORCID: https://orcid.org/0000-0002-5273-8088)
Institutions
- University of Helsinki (FI)
- Helsinki University Hospital (FI)
- Minerva Foundation (FI)
- Hospital District of Helsinki and Uusimaa (FI)
Publication Details
- Journal
- Thrombosis Journal
- Published
- 2024-09-05
- DOI
- https://doi.org/10.1186/s12959-024-00649-w
- Citations
- 4
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 1.14
Funders
- Helsingin Yliopisto