Neuromyelitis Optica Spectrum Disorder: A Case Report

Neuromyelitis optica spectrum disorder also known as Devic's disease is an autoimmune condition where the body produces antibodies against Aquaporin-4 in the astrocytes. This affects the brain and spinal cord leading to numerous manifestations like paralysis, transverse myelitis, and optic neuritis. MRI and aquaporin-4 antibody (AQP4-IgG) are crucial for its diagnosis. Treatment of the acute stage involves plasma exchange and intravenous steroids. Steroids and immune modulators can do long-term management. This case highlights a 40-year-old woman who manifested a wide range of neurological symptoms, including paralysis and eyesight loss. She had blood testing, radiology, and a clinical evaluation to diagnose her condition. Neuromyelitis optica spectrum disorder was diagnosed in light of the investigations. This instance emphasizes the need for careful examination and consideration of any paralysis. To prevent patients from experiencing psychological, financial, or physical challenges, treating physicians should be vigilant for any findings related to conditions like neuromyelitis optica spectrum disorder.

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Publication Details

Journal
Journal of Nepal Medical Association
Published
2024-08-31
DOI
https://doi.org/10.31729/jnma.8748
Citations
1
Primary Topic
Multiple Sclerosis Research Studies
Type
article
Field-Weighted Citation Impact
0.42
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article

Neuromyelitis Optica Spectrum Disorder: A Case Report

Kushal Poudel, Sagar Pahari, Nehal Asharaf, Nayan Neupane et al.
1 citations
Journal of Nepal Medical Association
Multiple Sclerosis Research Studies
0.42
article

Neuromyelitis Optica Spectrum Disorder: A Case Report

Kushal Poudel, Sagar Pahari, Nehal Asharaf, Nayan Neupane, Prakriti Karki
article en
1 citations

Abstract

Neuromyelitis optica spectrum disorder also known as Devic's disease is an autoimmune condition where the body produces antibodies against Aquaporin-4 in the astrocytes. This affects the brain and spinal cord leading to numerous manifestations like paralysis, transverse myelitis, and optic neuritis. MRI and aquaporin-4 antibody (AQP4-IgG) are crucial for its diagnosis. Treatment of the acute stage involves plasma exchange and intravenous steroids. Steroids and immune modulators can do long-term management. This case highlights a 40-year-old woman who manifested a wide range of neurological symptoms, including paralysis and eyesight loss. She had blood testing, radiology, and a clinical evaluation to diagnose her condition. Neuromyelitis optica spectrum disorder was diagnosed in light of the investigations. This instance emphasizes the need for careful examination and consideration of any paralysis. To prevent patients from experiencing psychological, financial, or physical challenges, treating physicians should be vigilant for any findings related to conditions like neuromyelitis optica spectrum disorder.

Journal of Nepal Medical AssociationVol. 62(277)
Nepal Medical College Teaching Hospital (NP), Bir Hospital (NP), Tribhuvan University Teaching Hospital (NP)
Good health and well-being
Openalex Percentile: Top 35%
Multiple Sclerosis Research Studies
0.42
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Neuromyelitis Optica Spectrum Disorder: A Case Report — Kushal Poudel, Sagar Pahari, et al. · Journal of Nepal Medical Association (2024) | TGRS Research Map | TGRS