Exploring first-degree family history in a cohort of Portuguese Alzheimer’s disease patients: population evidence for X-chromosome linked and recessive inheritance of risk factors
Our study gives evidence supporting an increased risk of developing AD associated with an X-linked inheritance pattern and remote consanguinity.
Authors
- Rita Guerreiro (ORCID: https://orcid.org/0000-0001-5879-3486)
- Kaitlyn Westra
- Jorge Rodrigues Saraiva (ORCID: https://orcid.org/0000-0001-9569-2334)
- João Durães (ORCID: https://orcid.org/0000-0001-9671-593X)
- Célia Kun‐Rodrigues (ORCID: https://orcid.org/0000-0003-4528-0061)
- José Brás (ORCID: https://orcid.org/0000-0001-8186-0333)
- Kimberly Paquette
- Miguel Tábuas‐Pereira (ORCID: https://orcid.org/0000-0002-3988-614X)
- Marisa Lima (ORCID: https://orcid.org/0000-0003-4200-9284)
- Maria Rosário Almeida (ORCID: https://orcid.org/0000-0002-1889-5469)
- Ana Rita Nogueira (ORCID: https://orcid.org/0000-0002-2005-1943)
- Inês Baldeiras (ORCID: https://orcid.org/0000-0002-8106-7308)
- Catarina Bernardes (ORCID: https://orcid.org/0009-0003-7322-2800)
- Mariana Coelho
- Teresa Tábuas
- Isabel Santana
Institutions
- Van Andel Institute (US)
- Hospitais da Universidade de Coimbra (PT)
- Universidade Politécnica de Bragança (PT)
- University of Coimbra (PT)
Publication Details
- Journal
- Journal of Neurology
- Published
- 2024-09-05
- DOI
- https://doi.org/10.1007/s00415-024-12673-x
- Citations
- 3
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.65
Funders
- National Institute on Aging