Evaluating the efficacy of endotracheal and intranasal epinephrine administration in severely asphyxic bradycardic newborn lambs: a randomised preclinical study
Our study supports neonatal resuscitation guidelines, highlighting intravenous administration as the most effective route for epinephrine. ET and IN epinephrine should only be considered when intravenous access is delayed or not feasible.
Authors
- Stuart B. Hooper (ORCID: https://orcid.org/0000-0003-1676-4825)
- Georg Marcus Schmölzer (ORCID: https://orcid.org/0000-0001-9798-2415)
- Robert Galinsky (ORCID: https://orcid.org/0000-0002-6374-9372)
- Graeme R. Polglase (ORCID: https://orcid.org/0000-0002-8906-614X)
- Nhi T. Tran (ORCID: https://orcid.org/0000-0002-0396-9760)
- Kelly J. Crossley (ORCID: https://orcid.org/0000-0002-1580-1156)
- Calum T. Roberts (ORCID: https://orcid.org/0000-0002-9111-5027)
- Justine de Jager (ORCID: https://orcid.org/0009-0008-7727-126X)
- Nils Thomas Songstad (ORCID: https://orcid.org/0000-0003-0343-5598)
- Claus Klingenberg (ORCID: https://orcid.org/0000-0001-6950-1573)
- Romy Pothof
- Arjan B te Pas
Institutions
- University Hospital of North Norway (NO)
- University of Alberta (CA)
- Leiden University Medical Center (NL)
- Hudson Institute of Medical Research (AU)
- Royal Alexandra Hospital (CA)
- Monash Children’s Hospital (AU)
- Monash University (AU)
- UiT The Arctic University of Norway (NO)
Publication Details
- Journal
- Archives of Disease in Childhood Fetal & Neonatal
- Published
- 2024-09-04
- DOI
- https://doi.org/10.1136/archdischild-2024-327348
- Citations
- 10
- Primary Topic
- Cardiac Arrest and Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 6.91
Funders
- National Heart Foundation of Australia
- State Government of Victoria
- Medical Research Council
- National Health and Medical Research Council