Differential interactions of Rickettsia species with tick microbiota in Rh. sanguineus and Rh. turanicus
Tick-borne rickettsioses, caused by Gram-negative bacteria of the Rickettsia genus, pose a growing global threat, with various arthropod vectors contributing to their transmission. Understanding the complex interactions within tick microbiota, including the role of Rickettsia species, is crucial for elucidating the dynamics of rickettsial diseases. Here, we investigate the taxonomic profiles and co-occurrence networks of Rickettsia in Rh. sanguineus sensus lato (s.l.) and Rh. turanicus ticks, revealing significant differences in community composition and local connectivity of Rickettsia species. While the microbiota of both tick species share common taxa, distinct differences in relative abundance and network topology suggest unique ecological niches. Moreover, robustness analysis demonstrates varying resilience to perturbations, indicating different strategies for network organization. Our findings also highlight metabolic differences between tick species, suggesting potential implications for Rickettsia interactions. Overall, this study provides insights into the intricate microbial landscape within ticks, shedding light on the functional redundancy and metabolic pathways associated with Rickettsia, thus advancing our understanding of tick-borne diseases.
Authors
- Dasiel Obregón (ORCID: https://orcid.org/0000-0002-5786-1114)
- Lourdes Mateos‐Hernández (ORCID: https://orcid.org/0000-0001-9566-7710)
- Myriam Kratou (ORCID: https://orcid.org/0009-0002-8962-2158)
- Alejandro Cabezas‐Cruz (ORCID: https://orcid.org/0000-0002-8660-730X)
- Consuelo Almazán (ORCID: https://orcid.org/0000-0003-3352-1745)
- Lianet Abuin‐Denis (ORCID: https://orcid.org/0009-0008-1305-3650)
- Juan Mosqueda (ORCID: https://orcid.org/0000-0001-8892-6390)
- Apolline Maître (ORCID: https://orcid.org/0000-0002-5586-9569)
- Mourad Ben Saïd (ORCID: https://orcid.org/0000-0001-5567-4721)
- Elianne Piloto‐Sardiñas (ORCID: https://orcid.org/0000-0002-6926-2194)
- Ivan Corona-Guerrero
Institutions
- Université de Corse Pascal Paoli (FR)
- Autonomous University of Queretaro (MX)
- École Nationale Vétérinaire d'Alfort (FR)
- Universidade de São Paulo (BR)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
- Universidade Cidade de São Paulo (BR)
- Centro Nacional de Sanidad Agropecuaria (CU)
- Bipar (FR)
- Systèmes d'Elevage Méditerranéens et Tropicaux - Laboratoire de Recherche sur le Développement de l'Elevage (FR)
- Centro de Ingeniería Genética y Biotecnología (CU)
- Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail (FR)
- ASL Environmental Sciences (Canada) (CA)
- Systèmes d’élevage méditerranéens et tropicaux (FR)
- University of Guelph (CA)
- Manouba University (TN)
Publication Details
- Journal
- Scientific Reports
- Published
- 2024-09-05
- DOI
- https://doi.org/10.1038/s41598-024-71539-4
- Citations
- 8
- Primary Topic
- Vector-borne infectious diseases
- Type
- article
- Field-Weighted Citation Impact
- 4.12
Funders
- Agence Nationale de la Recherche