A Concept for Mining Transitive Sequential Patterns from Pancreatic Cancer Patient Journeys
Pancreatic cancer, renowned for its aggressive nature and poor prognosis, necessitates the optimization of treatment strategies. The sequence of procedures in clinical trials is critical, such as evaluating the potential benefits of preoperative chemo-radio-therapy for pancreatic cancer. Nevertheless, we might not be aware of other temporal sequences which have an effect on therapy response or the general outcome. Extracting transitive sequential patterns from patients' medical trajectories allows researchers to identify temporal characteristics for complex diseases. We illustrate how such sequential patterns can be discovered and might be utilized in pancreatic cancer research as well as patient care.
Authors
- Ulrich Sax (ORCID: https://orcid.org/0000-0002-8188-3495)
- Elisabeth Heßmann (ORCID: https://orcid.org/0000-0002-9462-1291)
- Jonas Hügel (ORCID: https://orcid.org/0000-0002-4183-1287)
- Sophia Rheinländer (ORCID: https://orcid.org/0000-0002-5406-4427)
- Alexander König (ORCID: https://orcid.org/0009-0004-2039-7516)
- Jan Janosch Schneider (ORCID: https://orcid.org/0000-0001-8317-875X)
- Christoph Ammer-Hermenau
- Hossein Estiri
- Daniel T. Ortega
- Volker Ellenrieder
- Ella Maria Jentsch
- Nils Beyer
Institutions
- Harvard University (US)
- Massachusetts General Hospital (US)
- Universitätsmedizin Göttingen (DE)
- University of Göttingen (DE)
Publication Details
- Journal
- Studies in health technology and informatics
- Published
- 2024-08-30
- DOI
- https://doi.org/10.3233/shti240862
- Primary Topic
- Data Mining Algorithms and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00