A Concept for Mining Transitive Sequential Patterns from Pancreatic Cancer Patient Journeys

Pancreatic cancer, renowned for its aggressive nature and poor prognosis, necessitates the optimization of treatment strategies. The sequence of procedures in clinical trials is critical, such as evaluating the potential benefits of preoperative chemo-radio-therapy for pancreatic cancer. Nevertheless, we might not be aware of other temporal sequences which have an effect on therapy response or the general outcome. Extracting transitive sequential patterns from patients' medical trajectories allows researchers to identify temporal characteristics for complex diseases. We illustrate how such sequential patterns can be discovered and might be utilized in pancreatic cancer research as well as patient care.

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Publication Details

Journal
Studies in health technology and informatics
Published
2024-08-30
DOI
https://doi.org/10.3233/shti240862
Primary Topic
Data Mining Algorithms and Applications
Type
article
Field-Weighted Citation Impact
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article

A Concept for Mining Transitive Sequential Patterns from Pancreatic Cancer Patient Journeys

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Studies in health technology and informatics
Data Mining Algorithms and Applications
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A Concept for Mining Transitive Sequential Patterns from Pancreatic Cancer Patient Journeys

Ulrich Sax, Elisabeth Heßmann, Jonas Hügel, Sophia Rheinländer, Alexander König, Jan Janosch Schneider, Christoph Ammer-Hermenau, Hossein Estiri, Daniel T. Ortega, Volker Ellenrieder, Ella Maria Jentsch, Nils Beyer
article en

Abstract

Pancreatic cancer, renowned for its aggressive nature and poor prognosis, necessitates the optimization of treatment strategies. The sequence of procedures in clinical trials is critical, such as evaluating the potential benefits of preoperative chemo-radio-therapy for pancreatic cancer. Nevertheless, we might not be aware of other temporal sequences which have an effect on therapy response or the general outcome. Extracting transitive sequential patterns from patients' medical trajectories allows researchers to identify temporal characteristics for complex diseases. We illustrate how such sequential patterns can be discovered and might be utilized in pancreatic cancer research as well as patient care.

Studies in health technology and informaticsVol. 317
Harvard University (US), Massachusetts General Hospital (US), Universitätsmedizin Göttingen (DE), University of Göttingen (DE)
No poverty
Openalex Percentile: Top 62%
Data Mining Algorithms and Applications
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