Impaired TGF-β signaling via AHNAK family mutations elicits an esophageal cancer subtype with sensitivities to genotoxic therapy and immunotherapy
Our study extended our understanding of the AHNAK family in promoting GI and selecting treatment responders of ESCC.
Authors
- Hong Yang (ORCID: https://orcid.org/0000-0002-6007-9086)
- Xiuying Xie
- Lanlan Pang (ORCID: https://orcid.org/0000-0002-4932-8117)
- Jianhua Fu (ORCID: https://orcid.org/0000-0002-8544-1862)
- Zihang Mai (ORCID: https://orcid.org/0000-0002-4801-5004)
- Xinye Wang (ORCID: https://orcid.org/0000-0002-5776-7996)
- Jing Wen (ORCID: https://orcid.org/0000-0002-3227-8539)
- Luo Kongjia
Institutions
- Sun Yat-sen University (CN)
- Key Laboratory of Guangdong Province (CN)
- Sun Yat-sen University Cancer Center (CN)
Publication Details
- Journal
- Cancer Immunology Immunotherapy
- Published
- 2024-09-05
- DOI
- https://doi.org/10.1007/s00262-024-03798-z
- Citations
- 1
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.28
Funders
- National Natural Science Foundation of China