Identification of HDAC10 as a candidate oncogene in clear cell renal carcinoma that facilitates tumor proliferation and metastasis
Our study found the increased expression of HDAC10 was closely associated with poor prognosis of ccRCC patients. HDAC10 showed a pro-tumorigenic effect on ccRCC and promote the proliferation and metastasis of ccRCC, which may provide new light on targeted therapy for ccRCC.
Authors
- Qin Lei Wei (ORCID: https://orcid.org/0000-0002-3034-8046)
- Baojun Wang (ORCID: https://orcid.org/0000-0002-4858-8937)
- Xinran Chen (ORCID: https://orcid.org/0000-0001-7903-362X)
- Qingbo Huang (ORCID: https://orcid.org/0000-0003-2894-0187)
- Xin Ma (ORCID: https://orcid.org/0000-0002-7316-1468)
- Yang Yang (ORCID: https://orcid.org/0000-0001-6088-5435)
- Luojia Yang
Institutions
- Chinese PLA General Hospital (CN)
- Second Hospital of Shandong University (CN)
- Shanghai Clinical Research Center (CN)
Publication Details
- Journal
- Diagnostic Pathology
- Published
- 2024-09-05
- DOI
- https://doi.org/10.1186/s13000-024-01493-2
- Citations
- 2
- Primary Topic
- Histone Deacetylase Inhibitors Research
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- National Natural Science Foundation of China