LncSTPred: a predictive model of lncRNA subcellular localization and decipherment of the biological determinants influencing localization
By using our improved Adaboost algorithm, better prediction accuracy for lncRNA subcellular localization was obtained. In addition, we evaluated feature importance by using the F-score and analyzed the influence of highly relevant features on lncRNAs. Our study shows that the ANA features may be a key factor for predicting lncRNA subcellular localization, which correlates with the composition of stems and loops in the secondary structure of lncRNAs.
Authors
- Qian‐Zhong Li
- Jiahong Yang (ORCID: https://orcid.org/0000-0002-6839-534X)
- Sile Hu
- Lu-Qiang Zhang (ORCID: https://orcid.org/0000-0003-1236-957X)
- Yingli Chen (ORCID: https://orcid.org/0000-0003-0937-3375)
- Hui Bai
Institutions
- Inner Mongolia University (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2024-09-05
- DOI
- https://doi.org/10.3389/fmolb.2024.1452142
- Citations
- 1
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.29
Funders
- National Natural Science Foundation of China