High-dose chemotherapy with autologous stem cell transplants in adult primary non-seminoma mediastinal germ-cell tumors. A report from the Cellular Therapy and Immunobiology working party of the EBMT
To our knowledge, this is the most extensive retrospective study of HDC in PMNSGCTs patients and the first to thoroughly investigate potential predictors of benefit from this treatment. HDC with ASCT may well represent a therapeutic option in patients with PMNSGCTs after the first relapse or even as a front-line program.
Authors
- Myriam Labopin
- Gianantonio Rosti (ORCID: https://orcid.org/0000-0002-0310-4206)
- Jürgen Finke (ORCID: https://orcid.org/0000-0002-1799-5927)
- Ulrike Koehl (ORCID: https://orcid.org/0000-0002-8159-9160)
- Simona Secondino (ORCID: https://orcid.org/0000-0001-8839-139X)
- Alessia Pagani (ORCID: https://orcid.org/0000-0003-2374-4988)
- Florent Malard (ORCID: https://orcid.org/0000-0002-3474-0002)
- Jurgen H. E. Kuball (ORCID: https://orcid.org/0000-0002-3914-7806)
- Paolo Pedrazzoli (ORCID: https://orcid.org/0000-0002-9419-7160)
- Manuela Badoglio (ORCID: https://orcid.org/0000-0003-3226-2024)
- Ugo De Giorgi (ORCID: https://orcid.org/0000-0001-7520-2908)
- Christos Kosmas (ORCID: https://orcid.org/0000-0001-6790-5785)
- Christoph Seidel (ORCID: https://orcid.org/0000-0002-6023-6336)
- Carsten Bokemeyer (ORCID: https://orcid.org/0000-0001-6071-7810)
- Annalisa Ruggeri (ORCID: https://orcid.org/0000-0002-7261-2765)
- Elisabetta Metafuni (ORCID: https://orcid.org/0000-0002-4780-1273)
- Matthieu Delaye (ORCID: https://orcid.org/0000-0002-2435-4757)
- J-H Bouhris
- Edward Kanfer
Institutions
- Imperial College Healthcare NHS Trust (GB)
- Inserm (FR)
- Universität Hamburg (DE)
- University of Freiburg (DE)
- University of Pavia (IT)
- University Medical Center Freiburg (DE)
- Institut Gustave Roussy (FR)
- Agostino Gemelli University Polyclinic (IT)
- Sorbonne Université (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IT)
- Hôpital Saint-Antoine (FR)
- University Medical Center Hamburg-Eppendorf (DE)
- Metaxa Hospital (GR)
- Center for Translational Molecular Medicine (NL)
- Centre de Recherche Saint-Antoine (FR)
- Mylan (Switzerland) (CH)
- Fraunhofer Institute for Cell Therapy and Immunology (DE)
- Policlinico San Matteo Fondazione (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- European Society for Blood and Marrow Transplantation (FR)
- Hôpital Tenon (FR)
Publication Details
- Journal
- ESMO Open
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1016/j.esmoop.2024.103692
- Citations
- 7
- Primary Topic
- Testicular diseases and treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.01