Platinum-Catalyzed Deoxygenation of N-Acyloxyamines

Abstract We report a Pt-catalyzed double deoxygenative transformation of N-acyloxyamines, employing PtCl2 catalyst without external ligand under mild conditions. This method facilitates efficient C–N bond formation and can be used to synthesize a broad spectrum of alkylated secondary and tertiary amines with excellent yields. The adaptability and effectiveness of this approach highlight the potential of platinum catalysis to extend beyond traditional synthetic boundaries.