Causal effects of obstructive sleep apnea on chronic kidney disease and renal function: a bidirectional Mendelian randomization study
This MR study found no causal effect of OSA on renal function in Europeans. However, genetically predicted increased BUN is associated with OSA development. These findings indicate that the relationship between OSA and renal function remains elusive and requires further investigation.
Authors
- Zhenwei Xiao (ORCID: https://orcid.org/0000-0002-2263-4958)
- Zhenguo Wang (ORCID: https://orcid.org/0000-0002-3158-2002)
- Yawei Hou
- Yameng Li
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2024-09-04
- DOI
- https://doi.org/10.3389/fneur.2024.1323928
- Citations
- 2
- Primary Topic
- Obstructive Sleep Apnea Research
- Type
- article
- Field-Weighted Citation Impact
- 0.65