A pH-Responsive Drug-Delivery System Based on Apatinib-Loaded Metal-Organic Frameworks for Ferroptosis-Targeted Synergistic Anti-Tumor Therapy
We have successfully constructed a MOF delivery system with excellent safety, sustained-release capability, pH-targeting, and improved anti-tumor efficacy, highlighting its potential as a therapeutic approach for the treatment of HCC.
Authors
- Fangyi Peng
- Dongning Zheng (ORCID: https://orcid.org/0009-0008-9898-5982)
- Benjian Gao
- Shukui Qin (ORCID: https://orcid.org/0000-0003-2289-1521)
- Yang Jin (ORCID: https://orcid.org/0000-0003-2409-7073)
- Ming Luo (ORCID: https://orcid.org/0000-0002-3070-0927)
- Fengyi Yang (ORCID: https://orcid.org/0009-0000-7440-0013)
- Zhuo Chen (ORCID: https://orcid.org/0000-0002-3522-9660)
- Rui Wang (ORCID: https://orcid.org/0009-0008-2291-757X)
- Bo Li (ORCID: https://orcid.org/0000-0002-7979-8339)
- Xiaoli Yang (ORCID: https://orcid.org/0000-0002-8619-8489)
- Qiaoyan Dong
- Mengmei Nie
Institutions
- Southwest Medical University (CN)
- Affiliated Hospital of Southwest Medical University (CN)
- First Affiliated Hospital of Sichuan Medical University (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2024-09-01
- DOI
- https://doi.org/10.2147/ijn.s477248
- Citations
- 20
- Primary Topic
- Metal-Organic Frameworks: Synthesis and Applications
- Type
- article
- Field-Weighted Citation Impact
- 3.17