A randomized, placebo-controlled trial of purified anthocyanins on cognitive function in individuals at elevated risk for dementia: Analysis of inflammatory biomarkers toward personalized interventions
Individuals with elevated levels of inflammation markers benefited from anthocyanin treatment to enhance cognitive performance, whereas those with lower levels did not. The anti-inflammatory and antioxidant properties of anthocyanins make them a promising intervention, and future prospective trials in people with increased inflammation are warranted.
Authors
- Richard Siow (ORCID: https://orcid.org/0000-0003-4603-9763)
- Nicholas James Ashton (ORCID: https://orcid.org/0000-0002-3579-8804)
- George E. Barreto (ORCID: https://orcid.org/0000-0002-6644-1971)
- Anne Katrine Bergland
- Felipe Botero‐Rodríguez (ORCID: https://orcid.org/0000-0003-1537-5211)
- Chiara de Lucia (ORCID: https://orcid.org/0000-0002-7541-2814)
- Clive Ballard (ORCID: https://orcid.org/0000-0003-0022-5632)
- Khadija Khalifa
- Miguel Germán Borda (ORCID: https://orcid.org/0000-0001-5832-0603)
- Dag Aarsland (ORCID: https://orcid.org/0000-0001-6314-216X)
- Ilaria Pola (ORCID: https://orcid.org/0000-0003-2090-2944)
- Jonathan Patricio Baldera
- Miia Kivipelto (ORCID: https://orcid.org/0009-0001-1069-1787)
- Henrik Zetterberg
Institutions
- Universidad Autónoma de Santo Domingo (DO)
- University of Eastern Finland (FI)
- King's College London (GB)
- University of Limerick (IE)
- University of Exeter (GB)
- Stavanger University Hospital (NO)
- National Institute for Health and Care Research (GB)
- UK Dementia Research Institute (GB)
- Colciencias (CO)
- University College London (GB)
- University of Gothenburg (SE)
Publication Details
- Journal
- Experimental Gerontology
- Published
- 2024-09-09
- DOI
- https://doi.org/10.1016/j.exger.2024.112569
- Citations
- 11
- Primary Topic
- Neurological Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.72
Funders
- NordForsk