Tear levels of Transforming Growth Factor-β1 and Interleukin 1-β, and clinical correlations in new contact lens users

The presence of TGF-β1 in tears does not appear significantly affected by lens wear. The association between physiological parameters and IL1-β levels suggests that lenses may disrupt ocular surface homeostasis by altering cytokine regulatory mechanisms. However, due to its low concentration, IL1-β's role in the subclinical inflammatory response to lens wear is limited.

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Publication Details

Journal
Contact Lens and Anterior Eye
Published
2024-09-04
DOI
https://doi.org/10.1016/j.clae.2024.102299
Primary Topic
Ocular Surface and Contact Lens
Type
article
Field-Weighted Citation Impact
0.00

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article

Tear levels of Transforming Growth Factor-β1 and Interleukin 1-β, and clinical correlations in new contact lens users

Paula Sampaio, Eduardo Ínsua Pereira, Madalena Lira
Contact Lens and Anterior Eye
Ocular Surface and Contact Lens
article

Tear levels of Transforming Growth Factor-β1 and Interleukin 1-β, and clinical correlations in new contact lens users

Paula Sampaio, Eduardo Ínsua Pereira, Madalena Lira
article en

Abstract

The presence of TGF-β1 in tears does not appear significantly affected by lens wear. The association between physiological parameters and IL1-β levels suggests that lenses may disrupt ocular surface homeostasis by altering cytokine regulatory mechanisms. However, due to its low concentration, IL1-β's role in the subclinical inflammatory response to lens wear is limited.

Contact Lens and Anterior EyeVol. 47(6)
University of Minho (PT)
Fundação para a Ciência e a Tecnologia
Openalex Percentile: Top 78%
Ocular Surface and Contact Lens
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