Disseminated tumor cells in bone marrow as predictive classifiers for small cell lung cancer patients
Our findings suggest that bone marrow sampling and characterization of DTC subtypes provided a valuable tool for predicting treatment response and the prognosis in SCLC. Moreover, DTCs inherit a greater amount of homologous somatic information from pre-treatment CTCs, indicating their potential role in disease progression and treatment resistance.
Authors
- Peter Ping Lin (ORCID: https://orcid.org/0000-0002-6869-9490)
- Baohua Lu (ORCID: https://orcid.org/0000-0001-7715-9421)
- Jingying Nong (ORCID: https://orcid.org/0000-0002-0682-2190)
- Xingsheng Hu (ORCID: https://orcid.org/0000-0002-6652-2384)
- Jinjing Tan (ORCID: https://orcid.org/0000-0003-3534-8376)
- Yuan Gao (ORCID: https://orcid.org/0000-0002-7204-4438)
- Ying Wang (ORCID: https://orcid.org/0000-0002-1819-294X)
- Cen Chen (ORCID: https://orcid.org/0000-0003-1389-0148)
- Mingming Hu (ORCID: https://orcid.org/0000-0003-0021-0633)
- Xiaomei Yang (ORCID: https://orcid.org/0000-0002-4081-4207)
- Tongmei Zhang (ORCID: https://orcid.org/0000-0003-4271-3773)
- Lína Zhang (ORCID: https://orcid.org/0000-0003-3671-8690)
Institutions
- Capital Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Beijing Chest Hospital (CN)
- Shaanxi University of Chinese Medicine (CN)
- Cytel (United States) (US)
Publication Details
- Journal
- Journal of the National Cancer Center
- Published
- 2024-09-04
- DOI
- https://doi.org/10.1016/j.jncc.2024.07.003
- Citations
- 3
- Primary Topic
- Lung Cancer Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.85
Funders
- Beijing Municipal Science and Technology Commission