Haploidentical Stem Cell Transplantation With TCR αβ+/CD19+ Depletion in Children With Nonmalignant Hematologic Disorders: Outcomes From a Referral Center in Peru

The high incidence rates of graft failure and viral infections suggest that these factors may negatively impact the survival of children with nonmalignant hematologic disorders who undergo haplo-HSCT with TCR αβ+/CD19+ cell depletion. Therefore, optimizing the current conditioning regimens and ensuring timely access to first, second, and third-line antivirals is crucial to improve the survival of these patients.

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Publication Details

Journal
Transplantation Proceedings
Published
2024-09-04
DOI
https://doi.org/10.1016/j.transproceed.2024.08.038
Primary Topic
Hematopoietic Stem Cell Transplantation
Type
article
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article

Haploidentical Stem Cell Transplantation With TCR αβ+/CD19+ Depletion in Children With Nonmalignant Hematologic Disorders: Outcomes From a Referral Center in Peru

Sergio A Murillo-Vizcarra, Jackeline Carol Rodríguez-Torres, Pauline E Mamaní-Cajachagua, Alejandra Pando-Caciano
Transplantation Proceedings
Hematopoietic Stem Cell Transplantation
article

Haploidentical Stem Cell Transplantation With TCR αβ+/CD19+ Depletion in Children With Nonmalignant Hematologic Disorders: Outcomes From a Referral Center in Peru

Sergio A Murillo-Vizcarra, Jackeline Carol Rodríguez-Torres, Pauline E Mamaní-Cajachagua, Alejandra Pando-Caciano
article en

Abstract

The high incidence rates of graft failure and viral infections suggest that these factors may negatively impact the survival of children with nonmalignant hematologic disorders who undergo haplo-HSCT with TCR αβ+/CD19+ cell depletion. Therefore, optimizing the current conditioning regimens and ensuring timely access to first, second, and third-line antivirals is crucial to improve the survival of these patients.

Transplantation ProceedingsVol. 56(8)
Universidad Peruana Cayetano Heredia (PE), Hospital Nacional Cayetano Heredia (PE), Instituto Nacional de Salud del Niño (PE), St Martins Hospital (GB)
Zero hunger
Openalex Percentile: Top 77%
Hematopoietic Stem Cell Transplantation
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