Massive cerebral tuberculomas, Pott’s disease and hypercalcaemia secondary to <i>Mycobacterium bovis</i> in a patient with chronic kidney disease on peritoneal dialysis

Tuberculosis (TB) is still a health problem in developing countries. Pulmonary involvement remains the most common clinical presentation. However, multiorgan involvement can be life-threatening. We present the case of a young woman on peritoneal dialysis who was admitted to hospitalisation for hypercalcaemia and low back pain. In his biochemical evaluation, suppressed intact parthyroid hormone (iPTH) and elevated 1,25-hydroxyvitamin D were detected. On a lumbar CT scan, a hypodense lesion in vertebral bodies compatible with Pott's disease was found. Positive cultures for <i>Mycobacterium bovis</i> were obtained in bronchoalveolar lavage and peritoneal fluid, for which specific treatment was initiated. Due to neurological deterioration, a CT scan was performed showing the presence of multiple tuberculomas. Retrospectively, the lack of an etiological diagnosis of chronic kidney disease, the initiation of dialysis 8 months before and the clear evidence of long-standing TB strongly suggest mycobacterium infection as the cause or trigger for the rapid decline in kidney function.

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Publication Details

Journal
BMJ Case Reports
Published
2024-09-01
DOI
https://doi.org/10.1136/bcr-2024-261875
Primary Topic
Mycobacterium research and diagnosis
Type
article
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article

Massive cerebral tuberculomas, Pott’s disease and hypercalcaemia secondary to Mycobacterium bovis in a patient with chronic kidney disease on peritoneal dialysis

Carolina González-Fuentes, Mario Eduardo Alamilla Sanchez, Francisco Velasco García Lascurain, Juan Daniel Diaz Garcia
1 links
BMJ Case Reports
Mycobacterium research and diagnosis
article

Massive cerebral tuberculomas, Pott’s disease and hypercalcaemia secondary to Mycobacterium bovis in a patient with chronic kidney disease on peritoneal dialysis

Carolina González-Fuentes, Mario Eduardo Alamilla Sanchez, Francisco Velasco García Lascurain, Juan Daniel Diaz Garcia
article en

Abstract

Tuberculosis (TB) is still a health problem in developing countries. Pulmonary involvement remains the most common clinical presentation. However, multiorgan involvement can be life-threatening. We present the case of a young woman on peritoneal dialysis who was admitted to hospitalisation for hypercalcaemia and low back pain. In his biochemical evaluation, suppressed intact parthyroid hormone (iPTH) and elevated 1,25-hydroxyvitamin D were detected. On a lumbar CT scan, a hypodense lesion in vertebral bodies compatible with Pott's disease was found. Positive cultures for <i>Mycobacterium bovis</i> were obtained in bronchoalveolar lavage and peritoneal fluid, for which specific treatment was initiated. Due to neurological deterioration, a CT scan was performed showing the presence of multiple tuberculomas. Retrospectively, the lack of an etiological diagnosis of chronic kidney disease, the initiation of dialysis 8 months before and the clear evidence of long-standing TB strongly suggest mycobacterium infection as the cause or trigger for the rapid decline in kidney function.

BMJ Case ReportsVol. 17(9)
Centro Medico Nacional Siglo XXI (MX), Institute for Social Security and Services for State Workers (MX)
Partnerships for the goals
Openalex Percentile: Top 78%
Mycobacterium research and diagnosis
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