Massive cerebral tuberculomas, Pott’s disease and hypercalcaemia secondary to <i>Mycobacterium bovis</i> in a patient with chronic kidney disease on peritoneal dialysis
Tuberculosis (TB) is still a health problem in developing countries. Pulmonary involvement remains the most common clinical presentation. However, multiorgan involvement can be life-threatening. We present the case of a young woman on peritoneal dialysis who was admitted to hospitalisation for hypercalcaemia and low back pain. In his biochemical evaluation, suppressed intact parthyroid hormone (iPTH) and elevated 1,25-hydroxyvitamin D were detected. On a lumbar CT scan, a hypodense lesion in vertebral bodies compatible with Pott's disease was found. Positive cultures for <i>Mycobacterium bovis</i> were obtained in bronchoalveolar lavage and peritoneal fluid, for which specific treatment was initiated. Due to neurological deterioration, a CT scan was performed showing the presence of multiple tuberculomas. Retrospectively, the lack of an etiological diagnosis of chronic kidney disease, the initiation of dialysis 8 months before and the clear evidence of long-standing TB strongly suggest mycobacterium infection as the cause or trigger for the rapid decline in kidney function.
Authors
- Carolina González-Fuentes
- Mario Eduardo Alamilla Sanchez (ORCID: https://orcid.org/0000-0002-0678-5481)
- Francisco Velasco García Lascurain
- Juan Daniel Diaz Garcia (ORCID: https://orcid.org/0000-0002-5240-4782)
Institutions
- Centro Medico Nacional Siglo XXI (MX)
- Institute for Social Security and Services for State Workers (MX)
Publication Details
- Journal
- BMJ Case Reports
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1136/bcr-2024-261875
- Primary Topic
- Mycobacterium research and diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00