Luteolin as potential treatment for Huntington's disease: Insights from a transgenic mouse model

Luteolin holds promise as a therapeutic agent for improving survival outcomes, managing motor dysfunction, and reducing huntingtin aggregates in HD. The findings are of significance as currently, there are no approved therapeutic interventions that reverse HD pathology or slow down its progression.

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Publication Details

Journal
CNS Neuroscience & Therapeutics
Published
2024-09-01
DOI
https://doi.org/10.1111/cns.70025
Citations
5
Primary Topic
Genetic Neurodegenerative Diseases
Type
article
Field-Weighted Citation Impact
1.34
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article

Luteolin as potential treatment for Huntington's disease: Insights from a transgenic mouse model

Nadia Al Mazrouei, Vineetha Menon, Azza Ramadan, Fahad T. Alsulami et al.
5 citations
CNS Neuroscience & Therapeutics
Genetic Neurodegenerative Diseases
1.34
article

Luteolin as potential treatment for Huntington's disease: Insights from a transgenic mouse model

Nadia Al Mazrouei, Vineetha Menon, Azza Ramadan, Fahad T. Alsulami, Abdulla Al Amoodi, Ali Awadallah Saeed, Asim Ahmed Elnour, Sami Fatehi Abdalla, Yousef Saeed Alqarni, Abuelnor Mohammed
article en
5 citations

Abstract

Luteolin holds promise as a therapeutic agent for improving survival outcomes, managing motor dysfunction, and reducing huntingtin aggregates in HD. The findings are of significance as currently, there are no approved therapeutic interventions that reverse HD pathology or slow down its progression.

CNS Neuroscience & TherapeuticsVol. 30(9)
Alfaisal University (SA), Al Ain University (AE), Gulf Medical University (AE), Taif University (SA), University of Sharjah (AE), National University (SD), Abu Dhabi Health Services (AE), Dar Al Uloom University (SA), Almaarefa University, Huazhong University of Science and Technology (CN), Imam Abdulrahman Bin Faisal University (SA)
Good health and well-being
Openalex Percentile: Top 20%
Genetic Neurodegenerative Diseases
1.34
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Luteolin as potential treatment for Huntington's disease: Insights from a transgenic mouse model — Nadia Al Mazrouei, Vineetha Menon, et al. · CNS Neuroscience & Therapeutics (2024) | TGRS Research Map | TGRS