Antiviral Activity of Graphene Oxide–Silver Nanocomposites Against Murine Betacoronavirus
Graphene oxide sheets act as a stabilizing agent, inhibiting the accumulation of AgNPs and reducing their cellular toxicity. The GO-Ag composite can physically bind and inhibit murine betacoronavirus from entering cells. Furthermore, the constant presence of GO-Ag can inhibit MHV replication and significantly limit its extracellular release. In conclusion, GO-Ag shows promise as an antiviral coating on solid surfaces to minimize virus transmission and spread.
Authors
- Mateusz Wierzbicki (ORCID: https://orcid.org/0000-0003-3623-8929)
- Anna Słońska (ORCID: https://orcid.org/0000-0002-9872-3017)
- Marcin W. Bańbura (ORCID: https://orcid.org/0000-0002-4460-5031)
- Joanna Cymerys (ORCID: https://orcid.org/0000-0002-5273-3930)
- Ewa Sawosz (ORCID: https://orcid.org/0000-0002-0016-4721)
- Agata Lange (ORCID: https://orcid.org/0000-0003-1523-083X)
- Sławomir Jaworski (ORCID: https://orcid.org/0000-0002-4619-941X)
- Michalina Bartak (ORCID: https://orcid.org/0000-0001-5346-3760)
- Agnieszka Ostrowska (ORCID: https://orcid.org/0000-0001-8781-6106)
- Marcin Chodkowski (ORCID: https://orcid.org/0000-0002-2864-4356)
Institutions
- Warsaw University of Life Sciences (PL)
- Wojskowy Instytut Higieny i Epidemiologii (PL)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2024-09-01
- DOI
- https://doi.org/10.2147/ijn.s473448
- Citations
- 4
- Primary Topic
- Graphene and Nanomaterials Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.74