Non-invasive multimodal CT deep learning biomarker to predict pathological complete response of non-small cell lung cancer following neoadjuvant immunochemotherapy: a multicenter study
By extracting deep learning features from contrast enhanced and non-contrast enhanced CT, we constructed the LUNAI-fCT model as an imaging biomarker, which can non-invasively predict pathological complete response in neoadjuvant immunochemotherapy for NSCLC.
Authors
- Zhenwei Shi (ORCID: https://orcid.org/0000-0003-1305-5935)
- Leonard Wee (ORCID: https://orcid.org/0000-0003-1612-9055)
- Guanchao Ye (ORCID: https://orcid.org/0000-0003-4339-5922)
- André Dekker (ORCID: https://orcid.org/0000-0002-0422-7996)
- Chu Han (ORCID: https://orcid.org/0000-0001-7557-9131)
- Yongde Liao (ORCID: https://orcid.org/0000-0001-7989-2969)
- Kuo Li (ORCID: https://orcid.org/0000-0002-4859-6099)
- Chun‐yang Zhang (ORCID: https://orcid.org/0000-0002-8010-1981)
- Guangyao Wu (ORCID: https://orcid.org/0000-0002-3966-9268)
- Qi Yu (ORCID: https://orcid.org/0000-0001-7796-6899)
- Feng Li (ORCID: https://orcid.org/0009-0005-2823-3388)
- Mingliang Wang (ORCID: https://orcid.org/0000-0001-7497-819X)
- Zaiyi Liu (ORCID: https://orcid.org/0000-0002-9307-8522)
Institutions
- Maastricht University (NL)
- Key Laboratory of Guangdong Province (CN)
- Department of Health (TW)
- Wuhan Union Hospital (CN)
- Henan Provincial People's Hospital (CN)
- Guangdong Academy of Medical Sciences (CN)
- Guangdong Provincial People's Hospital (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
- Maastro Clinic (NL)
- Union Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Journal for ImmunoTherapy of Cancer
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1136/jitc-2024-009348
- Citations
- 34
- Primary Topic
- Radiomics and Machine Learning in Medical Imaging
- Type
- article
- Field-Weighted Citation Impact
- 13.75
Funders
- National Science Foundation
- National Natural Science Foundation of China
- Natural Science Foundation of Guangdong Province
- National Key Research and Development Program of China