<i>In Vitro</i> Oxidative Stress And Anticholinesterase Effects of Atorvastatin, Simvastatin, And Rosuvastatin in the Mouse Brain

Introduction: Hypolipidemic statins produce adverse neuronal effects, oxidative stress, and alterations of cholinesterase (ChE) activity. This in vitro study examined and ascertained effects of statins (atorvastatin, simvastatin, and rosuvastatin) on mice plasma and whole brain ChE activities and the oxidative stress marker brain malondialdehyde (MDA) level.

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Publication Details

Journal
Applied In Vitro Toxicology
Published
2024-09-01
DOI
https://doi.org/10.1089/aivt.2024.0032
Citations
2
Primary Topic
Computational Drug Discovery Methods
Type
article
Field-Weighted Citation Impact
0.72
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article

In Vitro Oxidative Stress And Anticholinesterase Effects of Atorvastatin, Simvastatin, And Rosuvastatin in the Mouse Brain

F. K. Mohammad, Rawnaq Faris Al-Shalchi
2 citations
Applied In Vitro Toxicology
Computational Drug Discovery Methods
0.72
article

In Vitro Oxidative Stress And Anticholinesterase Effects of Atorvastatin, Simvastatin, And Rosuvastatin in the Mouse Brain

F. K. Mohammad, Rawnaq Faris Al-Shalchi
article en
2 citations

Abstract

Introduction: Hypolipidemic statins produce adverse neuronal effects, oxidative stress, and alterations of cholinesterase (ChE) activity. This in vitro study examined and ascertained effects of statins (atorvastatin, simvastatin, and rosuvastatin) on mice plasma and whole brain ChE activities and the oxidative stress marker brain malondialdehyde (MDA) level.

Applied In Vitro ToxicologyVol. 10(3)
University of Mosul (IQ), University of Duhok (IQ)
Clean water and sanitation
Openalex Percentile: Top 26%
Computational Drug Discovery Methods
0.72
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