AGBL2 promotes renal cell carcinoma cells proliferation and migration via α-tubulin detyrosination
Our study suggests that AGBL2 fosters RCC cell proliferation and migration by enhancing α-tubulin detyrosination. Moreover, elevated AGBL2 expression increases phosphorylation of AKT in RCC cells.
Authors
- Binbin Gong
- Yifu Liu (ORCID: https://orcid.org/0000-0002-2018-2572)
- Yechen Nie
- Yifei Zhang (ORCID: https://orcid.org/0000-0003-0272-0602)
- Zhicheng Zhang (ORCID: https://orcid.org/0000-0002-6711-6425)
- Zhongqi Li (ORCID: https://orcid.org/0000-0001-8152-5033)
- Ming Ma
- Wei Liu
Institutions
- Nanchang University (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- First Affiliated Hospital of Nanchang University (CN)
Publication Details
- Journal
- Heliyon
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e37086
- Citations
- 1
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- Key Science and Technology Research Project in Jiangxi Province Department of Education