O25 eCLIPs implant in the endovascular treatment of wide neck aneurysms (WNBA)

<h3>Introduction</h3> eCLIPs combines both coil retention and flow diversion by bridging the neck of WNBA. We describe eCLIPs implant experience to date using 2 delivery systems: i) via hypotube with requisite .034’ microcatheter, eBRS, and ii) via guidewire, compatible with smaller microcatheters, eB. <h3>Aim of Study</h3> We report the entire eCLIPs experience for safety and efficacy: 280 patients, 101 eBRS and 179 eB. <h3>Methods</h3> Procedural data were collected prospectively and follow up data were collected according to usual clinical practices. <h3>Results</h3> Implant procedural success rate was 88%, 82% for eBRS, 92% for eB. 35% of cases were recurrences, 20% prior rupture. Anatomy: 89% cases were basilar tip and carotid terminus locations. Mean followup 38 mo: Safety: Procedural neurologic death: 3% eBRS, 0% eB (overall 1.1%), CVA 3% eBRS, 1.1% eB (overall 1.8%), repeat procedure (all with inadequate neck-bridging) 2.5%. No patient had post-procedural thrombo-embolic or other neurologic safety events. Efficacy: Of 82 patients with eBRS implants, 61 meet eligibility criteria for a WEB-IT-patterned trial; all available 57 patients of this cohort had follow-up imaging, many with multiple imaging timepoints. Forty patients with eB implants have had follow-up &gt; 6 months. Modified Raymond Roy Occlusion Classification (for all patients) 1 = 80%, 2 = 16%. No patient had regression of mRROC score on serial follow-up imaging. <h3>Conclusion</h3> eCLIPs has a satisfactory safety profile; introduction of lower-profile eCLIPs delivery system, eliminating large microcatheters and complex sidebranch access, resulted in lower procedural complications and improved procedural success. Durable adequate occlusion is 96%. <h3>Disclosure of Interest</h3> yes Co-founder Evasc Neurovascular.