Role of cerebrospinal fluid adenosine deaminase measurement in the diagnosis of tuberculous meningitis: an updated systematic review and meta-analysis
Studies remain heterogeneous but demonstrate that CSF ADA can differentiate TBM from non-TBM. In line with most studies, CSF ADA >10 IU/L supports the diagnosis of TBM in a patient with compatible symptoms and high-risk epidemiology.
Authors
- Tze Sian Liong
- Paul Anantharajah Tambyah (ORCID: https://orcid.org/0000-0003-0405-771X)
- Matthew Chung Yi Koh (ORCID: https://orcid.org/0009-0002-7374-8207)
- Priscillia Lye
- Jinghao Nicholas Ngiam (ORCID: https://orcid.org/0000-0002-3339-7281)
- Jyoti Somani (ORCID: https://orcid.org/0000-0002-4343-0145)
- Lizhen Ong (ORCID: https://orcid.org/0000-0003-1499-3640)
Institutions
- National University of Singapore (SG)
- National University Hospital (SG)
- National University Health System (SG)
Publication Details
- Journal
- Singapore Medical Journal
- Published
- 2024-09-03
- DOI
- https://doi.org/10.4103/singaporemedj.smj-2023-155
- Primary Topic
- Infectious Diseases and Tuberculosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00