Gut Microbial and Metabolic Features Associated With <i>Clostridioides difficile</i> Infection Recurrence in Children
Our study suggests that the differing gut microbiota profiles in pediatric CDI patients may contribute to disease recurrence by modulating SCFA concentrations and bile acid profiles. The gut microbiota and metabolite signatures may be used to predict disease recurrence in children with CDI.
Authors
- Dan Li (ORCID: https://orcid.org/0000-0002-1609-1539)
- Xiaolu Li (ORCID: https://orcid.org/0000-0002-9845-1584)
- Ting Zhang (ORCID: https://orcid.org/0000-0001-9391-8926)
- Lin Ye
- Yongmei Xiao (ORCID: https://orcid.org/0000-0002-8573-4171)
- Xufei Wang (ORCID: https://orcid.org/0000-0003-3761-7197)
- Yizhong Wang (ORCID: https://orcid.org/0000-0002-9390-8864)
- Fangfei Xiao
Institutions
- Shanghai Jiao Tong University (CN)
- Shanghai Children's Hospital (CN)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2024-08-30
- DOI
- https://doi.org/10.1093/ofid/ofae506
- Citations
- 2
- Primary Topic
- Clostridium difficile and Clostridium perfringens research
- Type
- article
- Field-Weighted Citation Impact
- 0.78
Funders
- Natural Science Foundation of Shanghai
- Shanghai Municipal Health Commission
- National Natural Science Foundation of China
- School of Medicine, Shanghai Jiao Tong University