BRCC36 regulates β-catenin ubiquitination to alleviate vascular calcification in chronic kidney disease
Our research results emphasize the critical role of the BRCC36-β-catenin axis in VC, suggesting that BRCC36 or β-catenin may be promising therapeutic targets to prevent the progression of VC in CKD patients.
Authors
- Huijuan Mao (ORCID: https://orcid.org/0000-0001-7410-1486)
- Xueqiang Xu (ORCID: https://orcid.org/0000-0001-8240-3521)
- Yiqing Xiong
- Caidie Xie (ORCID: https://orcid.org/0000-0001-7532-1421)
- Dongmei Liang (ORCID: https://orcid.org/0000-0003-1675-1960)
- Xiaoyue Chen
- Cheng Chen (ORCID: https://orcid.org/0000-0002-4509-9273)
- Yalan Li (ORCID: https://orcid.org/0000-0002-5885-3597)
- Min Min (ORCID: https://orcid.org/0009-0003-4191-6779)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Yangzhou Polytechnic Institute (CN)
- Jiangsu Province Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2024-09-03
- DOI
- https://doi.org/10.1186/s12967-024-05605-w
- Citations
- 5
- Primary Topic
- Dermatological and Skeletal Disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.75
Funders
- National Natural Science Foundation of China
- Priority Academic Program Development of Jiangsu Higher Education Institutions