The burden of tuberculosis among patients with non-small cell lung carcinoma in a tertiary care center
Total 75 patients with biopsy proven, primary NSCLC were recruited and 16 % (12/75) were diagnosed with confirmed TB. Adenocarcinoma (36.48 %) and Squamous cell carcinoma (33.44 %) were the two predominant histopathological subtypes of NSCLC. About 57 (76 %) of them were found to be in stage IV of Lung cancer at initial presentation itself (75 % in group A & 74.6 % in group B; p value < 0.80). A majority of patients (11/12 cases; 91 %) of group A were males with a mean age of 59 ± 7.5 years. The upper lobes of the lung were involved in 65 % (49/75) of the cases and showing a mass lesion on imaging (75 % in group A & 65 % in group B; p value < 0.52). Kaplan Meier survival revealed a median survival time of 11 months in subjects with only NSCLC and a median survival time of 4 months in the group with concomitant TB and NSCLC (p value < 0.44).
Authors
- Prabhat Singh Malik (ORCID: https://orcid.org/0000-0003-0205-8559)
- Urvashi B. Singh (ORCID: https://orcid.org/0000-0001-8753-9743)
- Kiran Bala (ORCID: https://orcid.org/0000-0002-8999-9070)
- Piyush Ranjan (ORCID: https://orcid.org/0000-0002-1754-1167)
- Niranjan Mahishi
- Arvind Kumar
- Anant Mohan
- Manish Soneja
Institutions
- All India Institute of Medical Sciences (IN)
Publication Details
- Journal
- Indian Journal of Medical Microbiology
- Published
- 2024-09-05
- DOI
- https://doi.org/10.1016/j.ijmmb.2024.100729
- Citations
- 1
- Primary Topic
- Tuberculosis Research and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.39