Oncostatin M promotes epithelial barrier dysfunction in patients with eosinophilic chronic rhinosinusitis with nasal polyps
OSM induces the synthesis and release of MMP-1 and -7 in NECs. Furthermore, MMP-1 and -7 promote mucosal epithelial barrier dysfunction in patients with Eos CRSwNP.
Authors
- Hai Lin (ORCID: https://orcid.org/0000-0001-8383-469X)
- Bao-Feng Wang
- Yun-Lan Yi (ORCID: https://orcid.org/0009-0009-8609-4303)
- Yingying Wang (ORCID: https://orcid.org/0000-0002-2455-1072)
Institutions
- Shanghai Jiao Tong University (CN)
- Shanghai Sixth People's Hospital (CN)
- Beijing Tsinghua Chang Gung Hospital (CN)
- Jining Medical University (CN)
- Jinzhou Medical University (CN)
- Tsinghua University (CN)
Publication Details
- Journal
- Tissue Barriers
- Published
- 2024-09-03
- DOI
- https://doi.org/10.1080/21688370.2024.2399235
- Citations
- 2
- Primary Topic
- Sinusitis and nasal conditions
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- National Natural Science Foundation of China