Epilepsy surgery below the age of 5 years: Are we still in time to preserve developmental and intellectual functions?
This retrospective study, conducted at the Bambino Gesù Children Hospital in Italy, reports neuropsychological and developmental and/or cognitive data for children undergoing early epilepsy surgery (before the age of 5). It found that children with lower developmental or cognitive profiles gained the highest scores on post-operative neuropsychological evaluations. This study provides information on the potential benefits of early surgery in shortening the duration of epilepsy, preventing or arresting deterioration, and enhancing plasticity and recovery.
Authors
- Luca De Palma (ORCID: https://orcid.org/0000-0002-0714-8230)
- Alessandro De Benedictis (ORCID: https://orcid.org/0000-0002-5414-198X)
- Chiara Pepi (ORCID: https://orcid.org/0000-0003-0880-6140)
- Federico Vigevano (ORCID: https://orcid.org/0000-0001-7513-0051)
- Mattia Mercier (ORCID: https://orcid.org/0000-0003-4239-8267)
- Daniela Chiarello (ORCID: https://orcid.org/0000-0002-0150-9453)
- Carlo Efisio Marras (ORCID: https://orcid.org/0000-0003-0790-8903)
- Chiara Falamesca (ORCID: https://orcid.org/0000-0001-8323-044X)
- Chiara Quintavalle (ORCID: https://orcid.org/0000-0001-8937-7805)
- Cinzia Correale (ORCID: https://orcid.org/0000-0002-9302-5412)
- Nicola Specchio (ORCID: https://orcid.org/0000-0002-8120-0287)
- Concetta Luisi (ORCID: https://orcid.org/0000-0003-2310-9992)
- Giusy Carfì Pavia (ORCID: https://orcid.org/0000-0001-5383-113X)
- Simona Cappelletti (ORCID: https://orcid.org/0000-0003-0738-1240)
Institutions
- Bambino Gesù Children's Hospital (IT)
- IRCCS Ospedale San Raffaele (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT)
Publication Details
- Journal
- Epilepsia Open
- Published
- 2024-09-02
- DOI
- https://doi.org/10.1002/epi4.13027
- Citations
- 3
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- Ministero della Salute