A SYSTEMATIC ANALYSIS FOR THE GLOBAL, REGIONAL AND LOCAL TREND OF BREAST CANCER, 1990-2019

The goal of this work is to perform a thorough investigation of the incidence, death and disability-adjusted life-years (DALYs) rates of breast cancer (BC) in local, regional, and worldwide contexts. It examines how variations in breast cancer incidence, death rates and DALYs are caused by elements including socioeconomic position, cultural norms and beliefs. Data were extracted from the Global Burden of Disease study 2019) and were calculated to quantify temporal trends in the age-standardized rates of BC incidence, deaths, and disability-adjusted life-years (DALYs) by region. From 1990 to 2019, the BC incidence, deaths, and DALYs increased worldwide by 128%, 84%, and 77%, respectively. The global age-standardized incidence rate increased, whereas both the age-standardized death rate and age-standardized DALY rate presented downward trends. In particular, Western Europe had the largest burden of BC, and globally, BC was more frequently reported in high-middle and high SDI regions. Expanding upon this thorough examination, the article suggests a range of focused, empirically supported tactics aimed at enabling healthcare decision-makers, physicians, and community leaders. Future BC preventive strategies should therefore focus on addressing the global health challenge of breast cancer, aiming to improve survival rates globally through the three pillars of health promotion, timely presentation and diagnosis, and comprehensive treatment and supportive care.