Effect of Prilocaine Infiltration into the Nephrostomy Tract After Percutaneous Nephrolithotomy on Postoperative Pain

Objective: To investigate the effect of local prilocaine infiltration on postoperative pain in patients undergoing percutaneous nephrolithotomy (PCNL). Materials and Methods: The case-control study enrolled 137 patients who underwent PCNL at Çukurova University Balcalı Hospital from April 2022 to December 2022. These patients were categorized into two distinct groups: The case and control groups. While peritubal 2% 10 cc prilocaine local anesthetic infiltration was applied to the cases, local anesthetic was not applied to the control group. Pain was evaluated using an analog scale after surgery. Results: In the study, which included 137 patients, local anesthesia was administered to 46 patients. Receiving local anesthesia was associated with the pain score (p<0.001). Pain scores were lower at the beginning and at the 4th minute in patients receiving local anesthesia (p<0.001 and p=0.004, respectively). Conclusion: Infiltration of peritubal prilocaine has been shown to notably diminish pain following PCNL. Our hypothesis suggests that local anesthetic infiltration into the nephrostomy tract could present a superior alternative for postoperative pain control. Nevertheless, extensive and prolonged follow-up studies are imperative for advancing research in this domain.