Effects of Perioperative Fluid Management on Endothelial Glycocalyx in Radical Cystectomy: A Randomized Clinical Trial
What's known on the subject? and What does the study add?Major abdominal surgeries are known to cause large amounts of fluid shifts in vivo, occasionally depending on the fluid therapy modality.Theoretically, excessive fluid replacement leads to glycocalyx damage; however, it is not well established how to follow-up such damage and its clinical implications.In this study, biochemical degradation products of glycocalyx and their relationship with liberal fluid therapy are demonstrated, although there may not be any clear change in hemodynamic monitoring.
Authors
- Fatma Savran Oğuz (ORCID: https://orcid.org/0000-0002-6018-8936)
- Emre Sertaç Bingül (ORCID: https://orcid.org/0000-0002-8662-5380)
- Kamil Tuğrul (ORCID: https://orcid.org/0000-0002-5155-2468)
- Selçuk Erdem (ORCID: https://orcid.org/0000-0002-3514-1394)
- Meltem Savran Karadeniz (ORCID: https://orcid.org/0000-0002-5663-1026)
- Hayriye Şentürk Çiftçi (ORCID: https://orcid.org/0000-0001-5160-5227)
- Burcu Kulaksız Mammadov
- Tural Mammadov
Institutions
- Istanbul Florence Nightingale Hospital (TR)
- Liv Hospital (TR)
- Türk Anesteziyoloji ve Reanimasyon Derneği (TR)
- Istanbul University (TR)
Publication Details
- Journal
- Journal of Urological Surgery
- Published
- 2024-09-03
- DOI
- https://doi.org/10.4274/jus.galenos.2024.2024-2-1
- Citations
- 1
- Primary Topic
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 0.42