Frequency of Renal Impairment Among Patients with Liver Cirrhosis with Spontaneous Bacterial Peritonitis

6and 30%.The development of spontaneous bacterial peritonitis (SBP) is associated with compromised humoral and cellular immune responses, leading to the migration of intestinal bacteria into the ascitic fluid.Spontaneous bacterial peritonitis (SBP) is further distinguished by its unfavorable long-term prognosis, as evidenced by a significant increase in mortality rates ranging from AbstractObjective: This study aim was to ascertain the prevalence of renal impairment among patients diagnosed with spontaneous bacterial peritonitis resulting from liver cirrhosis.Methods: The descriptive cross-sectional study was conducted in the Department of Gastroenterology, Hayatabad Medical Complex, located in Peshawar.The study duration was 6 months from September 29th, 2022 to March 29th, 2022.A cohort of 212 individuals was examined to ascertain the prevalence of renal dysfunction among patients afflected with spontaneous bacterial peritonitis because of liver cirrhosis.Results: A total of 212 patients were recruited in which 34.3% (n=72 ) were found in aged 31-40 years.The mean age of the participants was 51.53.3 years.Among total, 87 (41.4%) were male and 123 (58.6%) were female patients.Among total, 48 (22.9%) were found in underweight range.It was observed that 96 patients (45.7%) had renal impairment, while 114 patients (54.3%) not affected with renal impairment.The analysis revealed that smoking was seen in 80 individuals (38.1%), whereas hypertension was observed in 120 individuals (57.1%). Conclusion:Renal impairment has significant prevalent occurrence among cirrhotic patients presenting with ascites and spontaneous bacterial peritonitis (SBP).The SBP-RI variable has significant predictive value for hospital mortality in individuals diagnosed with SBP.Individuals who have significantly compromised liver function or pre-existing kidney failure are more susceptible to the development of spontaneous bacterial peritonitis with renal impairment.