Path Integration Detects Prodromal Alzheimer’s Disease and Predicts Cognitive Decline
Our results suggest that the 3D virtual reality navigation task detects prodromal AD patients and predicts cognitive decline after 12 months. Our navigation task, which is simple, short (12-15 minutes), noninvasive, and inexpensive, may be a screening tool for therapeutic choice of disease-modifiers in individuals with prodromal AD.
Authors
- Sadayoshi Watanabe (ORCID: https://orcid.org/0000-0001-5763-5849)
- Haruo Hanyu (ORCID: https://orcid.org/0000-0003-4411-335X)
- Riki Koike
- Hiroshi Matsuda (ORCID: https://orcid.org/0000-0002-6297-9897)
- Kazuki Umekida
- Akihiko Takashima
- Yumi Koyama
Institutions
- Fukushima Medical University (JP)
- Tokyo Medical University (JP)
- JR Tokyo General Hospital (JP)
- Gakushuin University (JP)
Publication Details
- Journal
- Journal of Alzheimer s Disease
- Published
- 2024-09-03
- DOI
- https://doi.org/10.3233/jad-240347
- Citations
- 6
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 2.31
Funders
- Japan Agency for Medical Research and Development