The impact of sex hormones on metabolic syndrome: univariable and multivariable Mendelian randomization studies
Our study indicates that SHBG is a protective factor for MetS, potentially delaying its onset and progression through improvements in HBP and TG. Furthermore, T and E2 may improve TG levels, with T also reducing WC levels. Importantly, our study provides new insights for the prevention and treatment of MetS.
Authors
- Yingying Xu (ORCID: https://orcid.org/0000-0003-4924-9379)
- Siyuan Liu (ORCID: https://orcid.org/0000-0002-7274-9155)
- Xinyi Chen (ORCID: https://orcid.org/0000-0002-3511-8733)
- Zhuosong Mu
Institutions
- Zhejiang Chinese Medical University (CN)
- Hangzhou Hospital of Traditional Chinese Medicine (CN)
- The Third Affiliated Hospital of Zhejiang Chinese Medical University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Diabetology & Metabolic Syndrome
- Published
- 2024-09-03
- DOI
- https://doi.org/10.1186/s13098-024-01443-4
- Citations
- 4
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 2.20