β-hydroxybutyrate and mitochondria mediate the association between medium-chain fatty acids, DHA and mild cognitive impairment: a nested case–control study
Higher serum octanoic acid and DHA levels were associated with lower MCI risk. Octanoic acid could affect the incidence of MCI through BHB, then mitochondria function, or through mitochondria function, or directly. Serum DHA level could affect the incidence of MCI through mitochondria function, or directly.
Authors
- Zhenshu Li (ORCID: https://orcid.org/0000-0002-0117-653X)
- Huilian Duan
- Ning Xu (ORCID: https://orcid.org/0000-0001-7909-7025)
- Guowei Huang (ORCID: https://orcid.org/0000-0002-0346-6303)
- Changqing Sun (ORCID: https://orcid.org/0000-0001-5509-9237)
- Jing Ying Yan (ORCID: https://orcid.org/0000-0001-8265-6270)
- Tong Yang
- Yongjie Chen (ORCID: https://orcid.org/0000-0002-9056-0604)
- Yuan Li (ORCID: https://orcid.org/0000-0003-0274-855X)
- Zehao Wang
- Yue Du (ORCID: https://orcid.org/0000-0001-5566-2341)
- Meilin Zhang (ORCID: https://orcid.org/0000-0001-8991-9133)
- Wen Li (ORCID: https://orcid.org/0000-0002-1747-9594)
- Guangshun Wang (ORCID: https://orcid.org/0000-0003-2769-3460)
- Fei Ma (ORCID: https://orcid.org/0000-0001-8554-7512)
- Xin Li (ORCID: https://orcid.org/0000-0001-6020-9170)
Institutions
- Second Hospital of Tianjin Medical University (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- Nutritional Neuroscience
- Published
- 2024-09-03
- DOI
- https://doi.org/10.1080/1028415x.2024.2398364
- Citations
- 2
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 0.65
Funders
- National Natural Science Foundation of China