Melatonin Mitigates Cisplatin-Induced Submandibular Gland Damage by Inhibiting Oxidative Stress, Inflammation, Apoptosis, and Fibrosis
Melatonin attenuated cisplatin-induced submandibular destruction alleviating SMG oxidative stress, inflammation, and fibrosis in addition to halting cellular apoptosis, sheds light on its usage in clinical application.
Authors
- Azza I. Helal
- Ahmed El-Metwally
- Ibrahim El-Shenbaby
- Amira E. Farage
- Medhat Taha (ORCID: https://orcid.org/0000-0001-8440-5002)
- Alaa M. Badawy
- Tourki A. S. Baokbah (ORCID: https://orcid.org/0000-0001-6091-198X)
- Emadeldeen Hussin
- Sara Abubakr
- Mohie Mahmoud Ibrahim (ORCID: https://orcid.org/0000-0001-8027-5298)
- Noha Hammad Sakr
Institutions
- Kafrelsheikh University (EG)
- Zarqa University (JO)
- Mansoura University (EG)
- Umm al-Qura University (SA)
Publication Details
- Journal
- Cureus
- Published
- 2024-09-03
- DOI
- https://doi.org/10.7759/cureus.68515
- Citations
- 2
- Primary Topic
- Chemotherapy-induced organ toxicity mitigation
- Type
- article
- Field-Weighted Citation Impact
- 0.85