Pelvic Sentinel Lymph Node Biopsy for Endometrial Cancer with Multi-Modal Infrared Signal Technology: A Video Article
This video article summarizes a case study involving the use of pelvic sentinel lymph node (SLN) biopsy for endometrial cancer (EC) staging and treatment utilizing a multi-modal infrared signal technology. This innovative approach combines cervical injection of fluorescent dye indocyanine green (ICG) and near-infrared imaging to enhance SLN detection rates in early-stage EC patients. The study showcases the successful application of advanced technology in improving surgical staging procedures and reducing postoperative morbidity for patients. Multi-modal infrared signal technology consists of different modes of fluorescence imaging used to identify lymph nodes based on near-infrared signals. Each mode serves a specific purpose: overlay image combines white light and near-infrared signals in green, monochromatic visualization shows near-infrared signal in greyscale, and intensity map combines signals in a color scale to differentiate signal intensity. Yellow denotes strong near-infrared signals while blue represents weaker signals. By utilizing a multi-modal approach, surgeons can accurately identify and remove SLN, thus avoiding unnecessary removal of secondary or tertiary echelons.
Authors
- Giulia Rovero (ORCID: https://orcid.org/0000-0003-3156-0484)
- Giovanni Scambia (ORCID: https://orcid.org/0000-0002-9503-9041)
- Emanuele Arturo Fera
- Giuseppe Vizzielli (ORCID: https://orcid.org/0000-0002-2424-2691)
- Anna Franca Cavaliere (ORCID: https://orcid.org/0000-0001-7484-5573)
- Gabriele Centini (ORCID: https://orcid.org/0000-0002-6113-7401)
- Martina Arcieri (ORCID: https://orcid.org/0000-0002-8257-0618)
- Federica Perelli (ORCID: https://orcid.org/0000-0002-5508-0875)
- Errico Zupi (ORCID: https://orcid.org/0000-0003-0735-6301)
- M Giusti
- Alberto Mattei
Institutions
- University of Siena (IT)
- Università Cattolica del Sacro Cuore (IT)
- Agostino Gemelli University Polyclinic (IT)
- Ospedale Santa Maria della Misericordia di Udine (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Azienda Usl Toscana Centro (IT)
Publication Details
- Journal
- Healthcare
- Published
- 2024-09-03
- DOI
- https://doi.org/10.3390/healthcare12171752
- Citations
- 2
- Primary Topic
- Endometrial and Cervical Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.17