Sepsis-Associated Acute Kidney Injury in Medical Intensive Care

Sepsis-associated acute kidney injury (SA-AKI), considered a common impediment of the critically sick patients and is linked with undesirable illness.Avoidance of SA-AKI can be achieved by prompt and plenty fluid restoration especially with crystalloid solutions.Meta-analysis revealed three basic phenomena contributing to SA-AKI that are microvascular dysfunction, inflammation, and metabolic reprogramming.